Dr. Jekyll, Mr. Hyde, and Omega-3s

By Josh Bloom — Nov 06, 2015
Omega 3 fatty acids (from fish oil) have been touted as a cure-all for pretty much every malady on the planet. With very rare exceptions, once studied properly, they end up being useless. If this depresses you, don't take fish oil. It just failed in a trial that examined whether it could treat depression. With commentary from ACSH advisor, Dr. David Seres.

Screen Shot 2015-11-06 at 12.33.39 PMAmerican Council on Science and Health advisor, Dr. David Seres, who is the is director of medical nutrition and associate professor of medicine at the Institute of Human Nutrition, Columbia University Medical Center in New York, is the first to admit that much of nutritional science is unreliable.

This is because many dietary studies are retrospective based on analysis of multiple past studies that were not designed to answer whatever question is being asked which makes accurate conclusions about what is "good" or "bad" to eat are very hard to come by.

Dr. Seres and I have written about omega-3 fatty acids from fish oil in the past, with regard to cardiovascular health (no benefit).

Now the supplements are in the news again, this time for treatment of depression. The results were, a let down. Not unlike the equivalent of Joe Dimaggio's 56 game hitting streak, omega 3s' streak continues. Except, this is 56 games without a hit.

Not surprisingly, Dr. Seres is less than sanguine when it comes down to whether there is any benefit whatsoever to adding fish oil to your diet, with one notable exception:

"We have seen some positive outcomes in rheumatic diseases. A derivative omega 3s called Lovazza works at pharmacological doses for treatment of hypertriglyceridemia (high levels of fat in the blood), but I am not sure if there's any solid data on outcomes in prevention of cardiovascular disease. Otherwise, it's not much more than an expensive source of calories. Nine grams per day of fish oil, which is the usual amount required to get enough omega 3 for any effect, is 81 calories. That's 8 pounds of weight gain every year."

With such a foul stench around this product, it might be time to throw this one back?

Josh Bloom

Director of Chemical and Pharmaceutical Science

Dr. Josh Bloom, the Director of Chemical and Pharmaceutical Science, comes from the world of drug discovery, where he did research for more than 20 years. He holds a Ph.D. in chemistry.

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